To Penetrate or Not to Penetrate...?

That is the anti-ageing question

Getting through the skin barrier is one of the major limiting factors of many cosmetics ingredients and it is not easy to know exactly how much of the active ingredient manages to penetrate the dermal barrier.

Most antiaging formulators of skin care products are exploring nano-technological solutions to making smaller molecules that can penetrate the stratum corneum, the outer most layer of the skin. Alternatively, other laboratories believe that the best method of restoring the youthful appearance of the skin lies in having the active ingredients ability to work from the skin's surface rather than having to cross the skin's barrier.

There is a chain of amino acids that is produced naturally in the upper layers of the skin. However, the production of the substance decreases with age, as does the body's response to it. It is a messenger molecule that sets off a pathway leading to the generation of extracellular matrix proteins such as elastin, fibronectin and collagen leading to skin renewal.

This polypeptide chain that binds to receptors on the skin's surface which will set off the pathway to skin rejuvenation has been recreated in the lab as one of the newest ingredients in effective skin renewal preparations.

"ARRESTAGE Laboratories Corporation has been perfecting it's anti-ageing serums to include liposomic molecular carriers as well as the top-down mode of action used by the aforementioned polypeptide chain making the ingredients 'exceptionally efficient' in comparison to other anti-ageing active ingredients we have used in our clinics", remarked Dr. Roy Shapiro a frequent lecturer in the Aesthetic Skin Care arena.

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